Article
Generation of pluripotent stem cells from neonatal mouse testis.
Cell - 29 Dec 2004
Kanatsu-Shinohara Mito, Inoue Kimiko, Lee Jiyoung, Yoshimoto Momoko, Ogonuki Narumi, Miki Hiromi, Baba Shiro, Kato Takeo, Kazuki Yasuhiro, Toyokuni Shinya, Toyoshima Megumi, Niwa Ohtsura, Oshimura Mitsuo, Heike Toshio, Nakahata Tatsutoshi, Ishino Fumitoshi, Ogura Atsuo, Shinohara Takashi
Abstract excerpt
Although germline cells can form multipotential embryonic stem (ES)/embryonic germ (EG) cells, these cells can be derived only from embryonic tissues, and such multipotent cells have not been available from neonatal gonads. Here we report the successful establishment of ES-like cells from neonatal mouse testis. These ES-like cells were phenotypically similar to ES/EG cells except in their genomic imprinting...
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