Article
Embryonic stem-derived versus somatic neural stem cells: a comparative analysis of their developmental potential and molecular phenotype.
Stem cells (Dayton, Ohio) - 1 Apr 2006
Colombo Elena, Giannelli Serena G, Galli Rossella, Tagliafico Enrico, Foroni Chiara, Tenedini Elena, Ferrari Sergio, Ferrari Stefano, Corte Giorgio, Vescovi Angelo, Cossu Giulio, Broccoli Vania
Abstract excerpt
Reliable procedures to induce neural commitment of totipotent undifferentiated embryonic stem (ES) cells have provided new tools for investigating the molecular mechanisms underlying cell fate choices. We extensively characterized the developmental potential of ES-induced neural cells obtained using an adaptation of the multistep induction protocol. We provided evidence that ES-derived neural proliferating cells...
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