Article
Functional dependence of neuroligin on a new non-PDZ intracellular domain.
Nature neuroscience - 1 Jun 2011
Shipman Seth L, Schnell Eric, Hirai Takaaki, Chen Bo-Shiun, Roche Katherine W, Nicoll Roger A
Abstract excerpt
Neuroligins, a family of postsynaptic adhesion molecules, are important in synaptogenesis through a well-characterized trans-synaptic interaction with neurexin. In addition, neuroligins are thought to drive postsynaptic assembly through binding of their intracellular domain to PSD-95. However, there is little direct evidence to support the functional necessity of the neuroligin intracellular domain in...
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