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Article

Temperature-sensitive mutants of Abelson murine leukemia virus deficient in protein tyrosine kinase activity.

Journal of virology - 1 Sept 1990

Engelman A, Rosenberg N

Abstract excerpt

The effect of two missense mutations in abl on transformation by Abelson murine leukemia virus was evaluated. These mutations led to the substitution of a histidine for Tyr-590 and a glycine for Lys-536. Both changes gave rise to strains that were temperature dependent for transformation of both NIH 3T3 cells and lymphoid cells when expressed in the context of a truncated Abelson protein. In the context of the...

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Identifiers

PMID: 1696637
DOI: 10.1128/JVI.64.9.4242-4251.1990
PMCID: PMC247889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Temperature-sensitive mutants of Abelson murine leukemia virus deficient in protein tyrosine kinase activity.PMID 1696637Read ↗

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