Simple assay based on restriction fragment length polymorphism associated with IL28B in chronic hepatitis C patients.

doi:10.3109/00365521.2011.574731

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Article

Simple assay based on restriction fragment length polymorphism associated with IL28B in chronic hepatitis C patients.

Scandinavian journal of gastroenterology - 1 Jul 2011

Nakamoto Shingo, Kanda Tatsuo, Imazeki Fumio, Wu Shuang, Arai Makoto, Fujiwara Keiichi, Yokosuka Osamu

Abstract excerpt

OBJECTIVE: Several studies recently revealed that single nucleotide polymorphisms (SNPs) in the interleukin28B (IL28B) region are associated with the response to pegylated interferon-alfa (PEG-IFN-alfa) and ribavirin (RBV) treatment among hepatitis C virus (HCV)-infected individuals of European, African and Asian ancestry. The purpose of the study was to establish methods for determining the SNP rs8099917...

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PMID: 21529139
DOI: 10.3109/00365521.2011.574731

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