Article
A tetra-primer amplification refractory mutation system polymerase chain reaction for the evaluation of rs12979860 IL28B genotype.
Journal of viral hepatitis - 1 Sept 2011
Galmozzi E, Del Menico B, Rametta R, Dongiovanni P, Fracanzani A L, Benedan L, Borroni V, Maggioni P, Fargion S, Valenti L
Abstract excerpt
Recently, genome-wide association studies in patients affected by HCV infection have identified a strong association between sustained virological response to peg-interferon/ribavirin and spontaneous viral clearance and common single nucleotide polymorphisms (SNPs) near the IL28B gene, encoding for interferon-lambda-3. Thus, it is anticipated that IL28B genotype determination will be integrated in clinical...
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