Article
IL28B SNP screening and distribution in the French Canadian population using a rapid PCR-based test.
Immunogenetics - 1 Jun 2013
Gélinas Jean-François, Fabre Thomas, Willems Philippe, Leung Reynold C, George Jacob, Willems Bernard, Bruneau Julie, Shoukry Naglaa H
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in the proximity of the interleukin-28B (IL28B) gene can predict spontaneous resolution of hepatitis C virus (HCV) infection and response to interferon therapy. Screening for this polymorphism has become part of the standard criteria for the management of HCV-infected patients, hence the need for a rapid, cost-effective screening method. Here, we describe a rapid PCR-based...
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