Article
Predicting sustained viral response to hepatitis C using a rapid and simple IL28B rs8099917 genotyping assay.
Antiviral research - 1 Apr 2012
Li Wei, Zeng Yanli, Wang Junjie, Zhou Bin, Zhang Jian, Zhang Hao, Li Jingtao, Wu Yingsong, Hamoudi Rifat, Zhou Yuanping
Abstract excerpt
Recent studies showed that two single nucleotide polymorphisms (SNPs) (rs12979860 and rs8099917) near the gene IL28B coding for IFNλ3 were associated with the antiviral treatment response of the combination therapy of pegIFN plus RBV. We established the use of tetra-primer amplification refractory mutation system polymerase chain reaction (ARMS-PCR) for detecting IL28B rs8099917 genotype (T>G) in 56 Chinese...
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