Article
A tetra-primer amplification refractory mutation system-polymerase chain reaction for the detection of rs8099917 IL28B genotype.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2012
Hashemi Mohammad, Moazeni-Roodi Abdolkarim, Bahari Ali, Taheri Mohsen
Abstract excerpt
Two single nucleotide polymorphisms (SNP, rs8099917, rs12979860) near the IL28B gene have been illustrated as outcome predictors of hepatitis C virus (HCV) treatment with pegylated interferon/ribavirin. The aim of the present study was to design a simple tetra-primer amplification refractory mutation system-polymerase chain reaction (T-ARMS-PCR) for the evaluation of the rs8099917 IL28B gene polymorphism. We...
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