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Article

Concomitant ABCG2 overexpression and FLT3-ITD mutation identify a subset of acute myeloid leukemia patients at high risk of relapse.

Cancer - 15 May 2011

Tiribelli Mario, Geromin Antonella, Michelutti Angela, Cavallin Margherita, Pianta Annalisa, Fabbro Dora, Russo Domenico, Damante Giuseppe, Fanin Renato, Damiani Daniela

Abstract excerpt

BACKGROUND: ABCG2 protein overexpression and FLT3 internal tandem duplication (ITD) correlate with higher relapse rate and shorter disease-free survival (DFS) in acute myeloid leukemia (AML), but no data are available on the possible effect of concomitant presence of these 2 factors. METHODS: The...

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Source

Identifiers

PMID: 21523728
DOI: 10.1002/cncr.25753

Genes

ABCG2
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21523728-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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