[Clinical Characteristics and Prognostic Relevance of Co-Mutated Genes in Acute Myeloid Leukemia Patients with FLT3 Mutations].

doi:10.19746/j.cnki.issn.1009-2137.2024.04.009

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[Clinical Characteristics and Prognostic Relevance of Co-Mutated Genes in Acute Myeloid Leukemia Patients with FLT3 Mutations].

Zhongguo shi yan xue ye xue za zhi - 1 Aug 2024

Chen Yang, Xie Yan-Yan, Fang Yu, Hong Ming, Liu Wen-Jie, Zhou Xuan, Zhang Wei, Shi Jin-Ning, Qian Si-Xuan

Abstract excerpt

OBJECTIVE: To investigate the clinical characteristics and influence of co-mutated gene on acute myeloid leukemia patients (AML) with FMS-like tyrosine kinase-3 (FLT3) mutations. METHODS: A total of 273 FLT3+ AML patients were enrolled, and the co-mutation gene data of the patients were collected to further analyze the prognosis of the patients. FLT3 and other common mutations were quantified by PCR amplification...

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PMID: 39192394
DOI: 10.19746/j.cnki.issn.1009-2137.2024.04.009

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