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Article

Co-expression of ATP binding cassette transporters is associated with poor prognosis in acute myeloid leukemia

21 Feb 2018

Abstract excerpt

Chemotherapy failure remains a challenge when treating patients with acute myeloid leukemia (AML), who often suffer from persistent or relapsed disease. The multidrug resistance (MDR) mediated by efflux transporters of the ATP binding cassette (ABC) superfamily is a major obstacle for successful chemotherapy. The present study aimed to elucidate whether the expression of ABC transporters was associated with...

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PMID: 29616130
DOI: 10.3892/ol.2018.8095

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