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Article

ABCG2 and CD200 define patients at high risk of relapse in ELN favorable subgroup of AML.

European journal of haematology - 1 Sept 2017

Tiribelli Mario, Geromin Antonella, Cavallin Margherita, Di Giusto Sara, Simeone Erica, Fanin Renato, Damiani Daniela

Abstract excerpt

OBJECTIVE: Overexpression of ABCG2 and CD200 has been independently associated with poor outcome in acute myeloid leukemia (AML). However, no data are available on the role of these two factors in patients with core-binding factor (CBF)-positive or FLT3-negative/NPM1-mutated cytogenetically normal (CN) AML. METHODS: We analyzed 65 adult AML patients with CBF+ (n=16) or FLT3-/NPM1+ CN (n=49), evaluating clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28618016
DOI: 10.1111/ejh.12915

Genes

ABCG2
ELN
FLT3
NPM1

Provenance

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