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Article

FLT3/ITD AML and the law of unintended consequences.

Blood - 30 Jun 2011

Levis Mark

Abstract excerpt

Acute myeloid leukemia with a FLT3 internal tandem duplication (FLT3/ITD) mutation is an aggressive hematologic malignancy with a generally poor prognosis. It can be successfully treated into remission with intensive chemotherapy, but it routinely relapses. At relapse, the blasts tend to have hig...

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Topics

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Share to fms-Like Tyrosine Kinase 3
Share to Gene Duplication
Share to Genes, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

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Source

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Identifiers

PMID: 21586749
DOI: 10.1182/blood-2011-03-340273
PMCID: PMC3143548

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21586749-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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