Article
Lack of influence of the ADH1B Arg47His genetic polymorphism on risk of colorectal adenoma in middle-aged Japanese men.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Yin Guang, Hamajima Nobuyuki, Morita Makiko, Tajima Osamu, Tabata Shinji, Kono Suminori
Abstract excerpt
Alcohol consumption is one of the risk factors for colorectal cancers and adenomas. Since alcohol dehydrogenase is a key enzyme in alcohol metabolism, it may thus play a role in colorectal carcinogenesis. The present study was conducted to assess the association of a functional ADH1B Arg47His polymorphism with colorectal adenomas in a case-control study of male officials in the Self-Defense Forces who received a...
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