Article
Genetic polymorphism and activities of human colon alcohol and aldehyde dehydrogenases: no gender and age differences.
Alcoholism, clinical and experimental research - 1 Oct 1994
Yin S J, Liao C S, Lee Y C, Wu C W, Jao S W
Abstract excerpt
Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) isoenzyme patterns from 69 (men, 47; women, 22) surgical colon mucosal specimens were identified by agarose isoelectric focusing. gamma-ADH was found to be the predominant form in the mucosa, whereas only beta-ADH was detectable in the muscle layer. ALDH1, ALDH2, and ALDH3 were detectable in the mucosa, with cytosolic ALDH1 being the major form. At pH...
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