Article
Relationships between cigarette smoking, alcohol drinking, the ALDH2 genotype and adenomatous types of colorectal polyps in male self-defense force officials.
Journal of epidemiology - 1 Nov 2000
Takeshita T, Morimoto K, Yamaguchi N, Watanabe S, Todoroki I, Honjo S, Nakagawa K, Kono S
Abstract excerpt
Alcohol drinking as well as cigarette smoking has been associated with development of colorectal polyps, Asians such, as Japanese, Chinese and Korean have high frequency of genetic polymorphism in low Km aldehyde dehydrogenase (ALDH2) gene which greatly regulates alcohol intake. In the present study, we investigated associations of this polymorphism and lifestyles with colorectal polyps in self-defense forces...
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