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Article

Common genetic variation in adiponectin, leptin, and leptin receptor and association with breast cancer subtypes.

Breast cancer research and treatment - 1 Sept 2011

Nyante Sarah J, Gammon Marilie D, Kaufman Jay S, Bensen Jeannette T, Lin Dan Yu, Barnholtz-Sloan Jill S, Hu Yijuan, He Qianchuan, Luo Jingchun, Millikan Robert C

Abstract excerpt

Adipocytokines are produced by visceral fat, and levels may be associated with breast cancer risk. We investigated whether single nucleotide polymorphisms (SNPs) in adipocytokine genes adiponectin (ADIPOQ), leptin (LEP), and the leptin receptor (LEPR) were associated with basal-like or luminal A breast cancer subtypes. 104 candidate and tag SNPs were genotyped in 1776 of 2022 controls and 1972 (200 basal-like,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21516303
DOI: 10.1007/s10549-011-1517-z
PMCID: PMC3355661

Genes

LEPR
ADIPOQ
LEP

Variants

rs1137100
rs1137100
rs1137100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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