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Article

Leptin and leptin receptor genes in relation to premenopausal breast cancer incidence and grade in Caucasian women.

Breast cancer research and treatment - 1 Jan 2012

Gu Fangyi, Kraft Peter, Rice Megan, Michels Karin B

Abstract excerpt

Body mass is inversely related to breast cancer risk among premenopausal women. Leptin, an essential cytokine regulating food intake, energy expenditure, glucose, and fat metabolism may be part of the mechanistic pathway. We investigated 50 tagging and candidate SNPs in the leptin (LEP) and leptin receptor (LEPR) genes for associations with premenopausal breast cancer incidence using 405 cases and 810 controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21947707
DOI: 10.1007/s10549-011-1778-6
PMCID: PMC3627481

Genes

LEPR
LEP

Variants

rs1137101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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