Article
Greater Body Fatness Is Associated With Higher Protein Expression of LEPR in Breast Tumor Tissues: A Cross-Sectional Analysis in the Women's Circle of Health Study.
Frontiers in endocrinology - 1 Jan 2022
Llanos Adana A M, Aremu John B, Cheng Ting-Yuan David, Chen Wenjin, Chekmareva Marina A, Cespedes Feliciano Elizabeth M, Qin Bo, Lin Yong, Omene Coral, Khoury Thaer, Hong Chi-Chen, Yao Song, Ambrosone Christine B, Bandera Elisa V, Demissie Kitaw
Abstract excerpt
Background: The mechanisms underlying the association of overall and central body fatness with poorer breast cancer outcomes remain unclear; altered gene and/or protein expression of the adipokines and their receptors in breast tumors might play a role. Methods: In a sample of Black and White women with primary invasive breast cancer, we investigated associations of body mass index (BMI), waist circumference, hip...
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