Article
Gene expression of adipokines and adipokine receptors in the tumor microenvironment: associations of lower expression with more aggressive breast tumor features.
Breast cancer research and treatment - 1 Feb 2021
Llanos Adana A M, Yao Song, Singh Amartya, Aremu John B, Khiabanian Hossein, Lin Yong, Omene Coral, Omilian Angela R, Khoury Thaer, Hong Chi-Chen, Ganesan Shridar, Foran David J, Higgins Michael J, Ambrosone Christine B, Bandera Elisa V, Demissie Kitaw
Abstract excerpt
PURPOSE: Limited epidemiologic data are available on the expression of adipokines leptin (LEP) and adiponectin (ADIPOQ) and adipokine receptors (LEPR, ADIPOR1, ADIPOR2) in the breast tumor microenvironment (TME). The associations of gene expression of these biomarkers with tumor clinicopathology are not well understood. METHODS: NanoString multiplexed assays were used to assess the gene expression levels of LEP,...
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