Article
Adiponectin pathway polymorphisms and risk of breast cancer in African Americans and Hispanics in the Women's Health Initiative.
Breast cancer research and treatment - 1 Jun 2013
Kaklamani Virginia G, Hoffmann Thomas J, Thornton Timothy A, Hayes Geoffrey, Chlebowski Rowan, Van Horn Linda, Mantzoros Christos
Abstract excerpt
Adiponectin, a protein secreted by the adipose tissue, is an endogenous insulin sensitizer with circulating levels that are decreased in obese and diabetic subjects. Recently, circulating levels of adiponectin have been correlated with breast cancer risk. Our previous work showed that polymorphisms of the adiponectin pathway are associated with breast cancer risk. We conducted the first study of adiponectin...
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