Article
New Advances in Polycystic Liver Diseases.
Seminars in liver disease - 1 Feb 2017
Santos-Laso A, Izquierdo-Sánchez L, Lee-Law P Y, Perugorria M J, Marzioni M, Marin J J G, Bujanda L, Banales J M
Abstract excerpt
Polycystic liver diseases (PLDs) include a heterogeneous group of congenital disorders inherited as dominant or recessive genetic traits; they are manifested alone or in association with polycystic kidney disease. Ductal plate malformation during embryogenesis and the loss of heterozygosity linked to second-hit mutations may promote the dilatation and/or development of a large number (> 20) of biliary cysts,...
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