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Therapeutic Targets in Polycystic Liver Disease

4 May 2017

Abstract excerpt

Polycystic liver diseases (PLD) are a group of genetic disorders initiated by mutations in several PLD-related genes and characterized by the presence of multiple cholangiocyte-derived hepatic cysts that progressively replace liver tissue. PLD co-exists with Autosomal Dominant Polycystic Kidney Disease (ADPKD) and Autosomal Recessive PKD as well as occurs alone (i.e., Autosomal Dominant Polycystic Liver Disease...

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PMID: 25915482
DOI: 10.2174/1389450116666150427161743

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