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Article

Primary Cilia in Hepatic Biliary Hyperplasia: Implications for Liver Diseases.

Seminars in liver disease - 1 Sept 2025

Pant Kishor, Peixoto Estanislao, Gradilone Sergio A

Abstract excerpt

Primary cilia, hair-like projections on the surface of various cell types, play crucial roles in sensing and regulating environmental cues within the liver, particularly among cholangiocytes. These structures detect changes in bile composition, flow, and other biochemical signals, integrating this information to modulate cellular processes. Dysfunction in cholangiocyte cilia-whether due to structural...

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Identifiers

PMID: 40118103
DOI: 10.1055/a-2563-9791
PMCID: PMC12790403

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