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Cholangiociliopathies: genetics, molecular mechanisms and potential therapies

1 May 2009

Abstract excerpt

PURPOSE OF REVIEW: The present review summarizes recent knowledge on polycystic liver diseases (PCLDs), mechanisms of hepatic cystogenesis and potential therapies for these conditions. RECENT FINDINGS: PCLD may be classified as cholangiociliopathies. In PCLD associated with polycystic kidney disease, cell proliferation is one of the major mechanisms of cystogenesis, whereas in isolated PCLD (autosomal dominant...

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PMID: 19349863
DOI: 10.1097/mog.0b013e328328f4ff

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