Article
Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.
BMC cancer - 22 Nov 2013
Vidal Adriana C, Tucker Cocoa, Schildkraut Joellen M, Richardson Ricardo M, McPhail Megan, Freedland Stephen J, Hoyo Cathrine, Grant Delores J
Abstract excerpt
BACKGROUND: We have previously shown that a functional polymorphism of the UGT2B15 gene (rs1902023) was associated with increased risk of prostate cancer (PC). Novel functional polymorphisms of the UGT2B17 and UGT2B15 genes have been recently characterized by in vitro assays but have not been evaluated in epidemiologic studies. METHODS: Fifteen functional SNPs of the UGT2B17 and UGT2B15 genes, including...
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