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Article

Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk.

Genetic testing and molecular biomarkers - 1 Jan 2013

Grant Delores J, Hoyo Cathrine, Oliver Shannon D, Gerber Leah, Shuler Katie, Calloway Elizabeth, Gaines Alexis R, McPhail Megan, Livingston Jonathan N, Richardson Ricardo M, Schildkraut Joellen M, Freedland Stephen J

Abstract excerpt

AIMS: Uridine diphosphate-glucuronosyltransferase 2B (UGT2B) enzymes conjugate testosterone metabolites to enable their excretion in humans. The functional significance of the UGT2B genetic variants has never been described in humans. We evaluated UGT2B variants in relation to plasma androstane-3α,17β-diol-glucuronide (AAG) levels and the prostate cancer risk. RESULTS: AAG levels were measured in sera from 150...

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Identifiers

PMID: 23098242
DOI: 10.1089/gtmb.2012.0161
PMCID: PMC3525886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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