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Article

Possible association between genetic variants in the H2AFX promoter region and risk of adult glioma in a Chinese Han population.

Journal of neuro-oncology - 1 Nov 2011

Fan Weiwei, Zhou Keke, Zhao Yingjie, Wu Wenting, Chen Hongyan, Jin Li, Chen Gong, Shi Jinlong, Wei Qingyi, Zhang Tianbao, Du Guhong, Mao Ying, Lu Daru, Zhou Liangfu

Abstract excerpt

H2AFX, a histone H2A gene family member X, is a key component in the detection of and response to DNA double-strand breaks (DSBs) caused by ionizing radiation (IR), a known risk factor for glioma. Thus, genetic variants in the H2AFX promoter region that may result in abnormal protein expression could confer susceptibility to glioma. In this case-control study, we genotyped three common single-nucleotide...

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Identifiers

PMID: 21512825
DOI: 10.1007/s11060-011-0586-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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