Article
MDM4 contributes to the increased risk of glioma susceptibility in Han Chinese population.
Scientific reports - 23 Jul 2018
Sun Peng, Yan Feng, Fang Wei, Zhao Junjie, Chen Hu, Ma Xudong, Song Jinning
Abstract excerpt
Recently, MDM4 gene has been reported to be a susceptibility gene for glioma in Europeans, but the molecular mechanism of glioma pathogenesis remains unknown. The aim of this study was to investigate whether common variants of MDM4 contribute to the risk of glioma in Han Chinese individuals. A total of 24 single-nucleotide polymorphisms (SNPs) of the MDM4 gene were assessed in a dataset of 562 glioma patients...
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