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Article

Genetic variation in H2AFX contributes to risk of non-Hodgkin lymphoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2007

Novik Karen L, Spinelli John J, Macarthur Amy C, Shumansky Karey, Sipahimalani Payal, Leach Stephen, Lai Agnes, Connors Joseph M, Gascoyne Randy D, Gallagher Richard P, Brooks-Wilson Angela R

Abstract excerpt

Non-Hodgkin lymphoma (NHL) comprises a group of lymphoid tumors that have in common somatic translocations. H2AFX encodes a key histone involved in the detection of the DNA double-stranded breaks that can lead to translocations. H2afx is a dosage-dependent gene that protects against B-cell lympho...

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PMID: 17548670
DOI: 10.1158/1055-9965.EPI-06-0639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17548670-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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