Article
Association between promoter variants of interleukin-18 and schizophrenia in a Han Chinese population.
DNA and cell biology - 1 Nov 2011
Liu Jinnan, Liu Jiaming, Zhou Yi, Li Siyue, Li Yi, Song Xingbo, Wang Jun, Wang Lanlan, Ying Binwu
Abstract excerpt
An increasing amount of evidence suggests that interleukin-18 (IL-18) plays a pivotal role in the pathophysiology of schizophrenia. However, association between single nucleotide polymorphism of IL-18 and the risk of schizophrenia has not been clarified. This study examined whether two promoter polymorphisms -137 G/C (rs187238) and -607 C/A (rs1946518) of IL-18 were associated with schizophrenia and six clinical...
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