Article
Lack of association of IL-6 (-174 G>C) and TNF-α (-238 G>A) variants with paranoid schizophrenia in Indian Bengalee population.
Cytokine - 1 Feb 2013
Debnath Monojit, Mitra Bikash, Bera Nirmal Kumar, Chaudhuri Tapas Kumar, Zhang Ya-ping
Abstract excerpt
Schizophrenia is a chronic debilitating neuropsychiatric disorder with complex etiopathology. Growing evidence suggests a significant role of chronic low grade inflammation in the pathophysiology of schizophrenia. Multiple immunological, genetic polymorphism and gene expression studies have established crucial roles of certain pro-inflammatory cytokines in the immune-mediated risk of schizophrenia. Although...
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