Article
Association of IL-18 promoter gene polymorphisms with rheumatoid arthritis: a meta-analysis.
Molecular biology reports - 1 Dec 2014
Cai Li-Ping, Zhou Li-Juan, Lu Shun-Yu, Liang Ying-E, Chen Xiao-Ying, Liu Lin, Lin Jun
Abstract excerpt
Interleukin-18(IL-18) plays a potential pathological role in rheumatoid arthritis (RA). The conclusions of the published reports on the relationship between single-nucleotide polymorphisms -607C/A (rs1946518) and -137G/C (rs187238) located in the IL-18 gene promoter and RA risk remain controversial. This meta-analysis was performed to evaluate the association between IL-18 gene promoter (-607A/C and -137C/G)...
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