Association of IL-18 polymorphisms with rheumatoid arthritis and systemic lupus erythematosus in Asian populations: a meta-analysis.

doi:10.1186/1471-2350-13-107

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Article

Association of IL-18 polymorphisms with rheumatoid arthritis and systemic lupus erythematosus in Asian populations: a meta-analysis.

BMC medical genetics - 15 Nov 2012

Chen Shuilian, Jiang Feng, Ren Jiangping, Liu Jiajing, Meng Wei

Abstract excerpt

BACKGROUND: Interleukin (IL)-18, an important proinflammatory cytokine, plays a potential pathological role in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Studies on the relationship of IL-18 gene promoter rs1946518 (-607A/C) polymorphism, rs187238 (-137G/C) polymorphism with RA and SLE are inconclusive. The aim of this study was to get a more precise estimation of the relationship in Asian...

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PMID: 23153245
DOI: 10.1186/1471-2350-13-107
PMCID: PMC3523015

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