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Article

ATA homozigosity in the IL-10 gene promoter is a risk factor for schizophrenia in Spanish females: a case control study.

BMC medical genetics - 9 Jun 2011

Almoguera Berta, Riveiro-Alvarez Rosa, Lopez-Castroman Jorge, Dorado Pedro, Lopez-Rodriguez Rosario, Fernandez-Navarro Pablo, Baca-García Enrique, Fernandez-Piqueras Jose, Dal-Ré Rafael, Abad-Santos Francisco, Llerena Adrián, Ayuso Carmen

Abstract excerpt

BACKGROUND: Three IL-10 gene promoter single nucleotide polymorphisms -1082G > A, -819C > T and -592C > A and the haplotypes they define in Caucasians, GCC, ACC, ATA, associated with different IL-10 production rates, have been linked to schizophrenia in some populations with conflicting results. On the basis of the evidence of the sex-dependent effect of certain genes in many complex diseases, we conducted a...

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Identifiers

PMID: 21658228
DOI: 10.1186/1471-2350-12-81
PMCID: PMC3144450

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Source receipt: pubmed, retrieved 7 Sept 2026.

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