Article
IL-10 promoter genetic polymorphisms and risk of Kawasaki disease in Taiwan.
Disease markers - 1 Jan 2011
Hsieh Kai-Sheng, Lai Tsung-Jen, Hwang Yu-Tung, Lin Ming-Wei, Weng Ken-Pen, Chiu Yi-Ten, Ho Tsyr-Yuh, Chen Chi-Shan, Shiue Yow-Ling, Hsiao Michael, Tsai Shih-Feng, Ger Luo-Ping
Abstract excerpt
Kawasaki disease (KD) is the most common cause of pediatric acquired heart disease. KD patients have spontaneously high plasma/serum levels of IL-10 during the acute phase. Therefore, two independent studies were carried out to investigate the association between genetic variants in IL-10 promoter (-1082, -819, and -592) and risk of KD. A total of 134 trios were included for the family-based association study. A...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
