Article
The -590 C/T and 8375 A/G interleukin-4 polymorphisms are not associated with Kawasaki disease in Taiwanese children.
Human immunology - 1 Jan 2008
Huang Fu-Yuan, Chang Tzu-Yang, Chen Ming-Ren, Lee Hung-Chang, Chiu Nan-Chang, Chi Hsin, Hsu Chyong-Hsin, Lin Shuan-Pei, Liu Hsin-Fu, Chen Wei-Fang, Chu Chen-Chung, Lin Marie, Lee Yann-Jinn
Abstract excerpt
Although some previous studies have reported that genetic and immunologic factors play important roles in the pathogenesis of Kawasaki disease (KD), the etiologic factors of this enigmatical pediatric disease are still poorly understood. This study aims to investigate whether polymorphisms of the interleukin-4 gene (IL-4; -590 C/T in the promoter region and 8375 A/G in intron 3) are associated with KD and the...
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