Article
Genetics of Kawasaki disease: what we know and don't know.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2012
Onouchi Yoshihiro
Abstract excerpt
Kawasaki disease (KD) is a leading cause of acquired heart disease in children in developed countries. Although it has been thought that symptoms of KD are related to hyperactivation of the immune system triggered by infection with some microorganisms, the etiological agent still remains unknown. In this situation, genetic factors underlying the disease pathogenesis, which have been suggested by epidemiological...
Topics
- Animals
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Mucocutaneous Lymph Node Syndrome
- Phenotype
- Polymorphism, Single Nucleotide
- Prognosis
- Risk Assessment
- Risk Factors