[Research advances in genetic polymorphisms in Kawasaki disease].

Abstract excerpt

Kawasaki disease (KD) is a systemic inflammatory vascular disorder that predominantly affects children and is the leading cause of acquired heart disease in children. Although the etiology of this disease remains unclear, genome-wide association and genome-wide linkage studies have shown that some susceptible genes and chromosomal regions are associated with the development and progression of KD. With the...

Topics

• Child
• Humans
• Mucocutaneous Lymph Node Syndrome
• Genome-Wide Association Study
• Genetic Predisposition to Disease
• Polymorphism, Genetic
• Coronary Vessels
• Polymorphism, Single Nucleotide