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Article

Influence of interleukin 18 promoter polymorphisms in susceptibility to Kawasaki disease in Taiwan.

The Journal of rheumatology - 1 Jul 2008

Hsueh Kai-Chung, Lin Ying-Ju, Chang Jeng-Sheng, Wan Lei, Tsai Yu-Hsin, Tsai Chang-Hai, Tsai Fuu-Jen

Abstract excerpt

OBJECTIVE: Proinflammatory cytokines such as interferon-gamma (IFN-gamma) play an important role in the pathogenesis of Kawasaki disease (KD). Interleukin 18 (IL-18) plays a pivotal role in the T helper 1 (Th1)-type response, principally owing to its ability to induce IFN-gamma production. We assessed potential associations between functional IL-18 gene promoter polymorphisms and susceptibility to KD, in addition...

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PMID: 18484687

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GCG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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