Article
Interleukin-4 cytokine single nucleotide polymorphisms in kawasaki disease: a case-control study and a review of knowledge.
International journal of rheumatic diseases - 1 Jan 2018
Assari Raheleh, Aghighi Yahya, Ziaee Vahid, Sadr Maryam, Rezaei Arezou, Rahmani Farzaneh, Sadr Zeinab, Raeeskarami Seyed Reza, Moradinejad Mohammad Hassan, Rezaei Nima
Abstract excerpt
AIM: Kawasaki disease (KD) is a systemic vasculitis of medium-sized arteries. High levels of interleukin 4 (IL-4) and the dominance of Th2 cytokines seem to be a key feature in the acute phase of KD. In this study, the role of IL-4 and IL-4R gene polymorphisms were investigated in Iranian children with KD. METHODS: Fifty-five patients with KD and 140 healthy subjects as a control group were enrolled in this...
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