Article
Interleukin-4 cytokine single nucleotide polymorphisms in kawasaki disease: a case-control study and a review of knowledge.
International journal of rheumatic diseases - 1 Jan 2018
Assari Raheleh, Aghighi Yahya, Ziaee Vahid, Sadr Maryam, Rezaei Arezou, Rahmani Farzaneh, Sadr Zeinab, Raeeskarami Seyed Reza, Moradinejad Mohammad Hassan, Rezaei Nima
Abstract excerpt
AIM: Kawasaki disease (KD) is a systemic vasculitis of medium-sized arteries. High levels of interleukin 4 (IL-4) and the dominance of Th2 cytokines seem to be a key feature in the acute phase of KD. In this study, the role of IL-4 and IL-4R gene polymorphisms were investigated in Iranian childre...
Topics
- Age Factors
- Case-Control Studies
- Child, Preschool
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Haplotypes
- Heterozygote
- Homozygote
- Humans
- Infant
- Interleukin-4
- Interleukin-4 Receptor alpha Subunit