Article
Association of interleukin-10 A-592C polymorphism in Taiwanese children with Kawasaki disease.
Journal of Korean medical science - 1 Jun 2009
Hsueh Kai-Chung, Lin Ying-Ju, Chang Jeng-Sheng, Wan Lei, Tsai Yu-Hsin, Tsai Chang-Hai, Chen Chih-Ping, Tsai Fuu-Jen
Abstract excerpt
Elevated serum levels of interleukin-10 (IL-10) have been reported in patients with Kawasaki disease (KD). IL-10 reduces the inflammatory actions of macrophages and T cells and it may play a significant role in the regulation of inflammatory vascular damage associated with systemic vasculitis. The aim of this study was to examine whether -592 IL-10 promoter polymorphism is a susceptibility or severity marker of...
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