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Article

Single nucleotide polymorphisms of integrin alpha-2 and beta-3 genes are not associated with relapse-free and overall survival in colorectal cancer patients.

Anticancer research - 1 Apr 2011

Hofmann Günter, Langsenlehner Uwe, Langsenlehner Tanja, Glehr Matthias, Gerger Armin, Absenger Gudrun, Szkandera Joanna, Fuerst Florentine, Samonigg Hellmut, Krippl Peter, Renner Wilfried

Abstract excerpt

BACKGROUND: Integrins influence tumourigenesis, tumor progression and development of metastases. The impact of polymorphisms in integrin genes on relapse-free survival (RFS) and overall survival (OS) for 433 Caucasian patients with colorectal cancer was analysed in this retrospective study. PATIENTS AND METHODS: A Cox regression model including integrin genotype, age, grading, tumour size, number of lymph nodes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21508388

Genes

ITGA2
ITGB3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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