Relationship between chromosome 18q status and colorectal cancer prognosis: a prospective, blinded analysis of 280 patients.

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Article

Relationship between chromosome 18q status and colorectal cancer prognosis: a prospective, blinded analysis of 280 patients.

Anticancer research - 1 Jan 2000

Popat Sanjay, Zhao Dongbing, Chen Zhengming, Pan Hongchao, Shao Yongfu, Chandler Ian, Houlston Richard S

Abstract excerpt

BACKGROUND: The relationship between chromosome 18q allelic imbalance (AI) and survival in colorectal cancer (CRC) is unclear, and study design may have contributed to inconsistent results previously reported. PATIENTS AND METHODS: Two hundred and eighty tumours from CRC patients participating in a molecular sub-study from a single multicentre trial of adjuvant intra-portal 5-fluorouracil were genotyped at 5...

Topics

Adolescent
Adult
Aged
Allelic Imbalance
Chromosomes, Human, Pair 18
Colorectal Neoplasms
Double-Blind Method
Female
Genotype
Humans
Kaplan-Meier Estimate
Male
Microsatellite Repeats
Middle Aged
Prognosis
Prospective Studies

Source

Open in PubMed

Identifiers

PMID: 17348452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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