Article
TS gene polymorphisms are not good markers of response to 5-FU therapy in stage III colon cancer patients.
Analytical cellular pathology (Amsterdam) - 1 Jan 2010
Fariña-Sarasqueta A, Gosens M J E M, Moerland E, van Lijnschoten I, Lemmens V E P P, Slooter G D, Rutten H J T, van den Brule A J C
Abstract excerpt
AIM: Although the predictive and prognostic value of thymidylate synthase (TS) expression and gene polymorphism in colon cancer has been widely studied, the results are inconclusive probably because of methodological differences. With this study, we aimed to elucidate the role of TS gene polymorp...
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