Article
LD1: a CD4-CD8- TCR alpha beta/CD3+ peripheral T cell line with helper function for B lymphocytes.
International immunology - 1 Jan 1990
Pelkonen J, Palacios R
Abstract excerpt
In order to learn more about the small subset of CD4-CD8- TCR alpha beta/CD3+ peripheral T lymphocytes, we firstly characterized at the cellular and molecular levels the CD4-CD8- LD1 cell line isolated from the spleen of an MRL/lpr-lpr mouse. Secondly we studied its functional properties. LD1 cel...
Topics
- Animals
- Antigens, Differentiation, T-Lymphocyte
- B-Lymphocytes
- CD3 Complex
- CD4 Antigens
- CD8 Antigens
- Cell Differentiation
- Cell Line
- Cytokines
- Cytotoxicity, Immunologic
- Female
- Male
- Mice
- Mice, Inbred Strains
- Phenotype
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell, alpha-beta
- T-Lymphocyte Subsets