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Article

Clinical relevance of VKORC1 (G-1639A and C1173T) and CYP2C9*3 among patients on warfarin.

Journal of clinical pharmacy and therapeutics - 1 Apr 2012

Teh L K, Langmia I M, Fazleen Haslinda M H, Ngow H A, Roziah M J, Harun R, Zakaria Z A, Salleh M Z

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVES: Testing for cytochrome P450-2C9 (CYP2C9) and vitamin K epoxide reductase complex subunit 1 (VKORC1) variant alleles is recommended by the FDA for dosing of warfarin. However, dose prediction models derived from data obtained in one population may not be applicable to another. We therefore studied the impact of genetic polymorphisms of CYP2C9 and VKORC1 on warfarin dose requirement in...

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Source

Identifiers

PMID: 21507031
DOI: 10.1111/j.1365-2710.2011.01262.x

Genes

VKORC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clinical relevance of VKORC1 (G-1639A and C1173T) and CYP2C9*3 among patients on warfarin.PMID 21507031Read ↗

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