Article
Fibronectin receptor overexpression and loss of transformed phenotype in a stable variant of the K562 cell line.
Cell regulation - 1 Aug 1990
Symington B E
Abstract excerpt
A variant of the K562 erythroleukemia cell line, FA-K562, was selected by cycles of adhesion to solid-phase plasma fibronectin (FN). FA-K562 expresses fourfold more cell-surface alpha 5 beta 1 fibronectin receptor (FNR) than parental K562. In addition to expected differences in adhesion to FN, other differences between FA-K562 and K562 implicate this FNR in the regulation of cell growth and morphology. FA-K562...
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