Article
Fibronectin receptor overexpression and loss of transformed phenotype in a stable variant of the K562 cell line.
Cell regulation - 1 Aug 1990
Symington B E
Abstract excerpt
A variant of the K562 erythroleukemia cell line, FA-K562, was selected by cycles of adhesion to solid-phase plasma fibronectin (FN). FA-K562 expresses fourfold more cell-surface alpha 5 beta 1 fibronectin receptor (FNR) than parental K562. In addition to expected differences in adhesion to FN, ot...
Topics
- Actins
- Animals
- Cell Adhesion
- Cell Differentiation
- Cell Transformation, Neoplastic
- Cytoskeleton
- Fibronectins
- Fluorescent Antibody Technique
- Humans
- Mice
- Mice, Nude
- Neoplasm Metastasis
- Neoplasm Transplantation
- Phenotype
- Receptors, Fibronectin
- Receptors, Immunologic
- Tumor Cells, Cultured
- Vimentin