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Article

Defective vasculature in fibronectin-receptor-deficient CHO cell tumors in nude mice.

International journal of cancer - 30 Sept 1993

Schreiner C L, Fisher M, Bauer J, Juliano R L

Abstract excerpt

The level of expression of the alpha 5/beta 1 integrin fibronectin receptor (FnR) strongly affects the growth rate of CHO cell tumors in nude mice. Here we report that alpha 5/beta 1 expression also influences the organization of the tumor vasculature. Tumors formed from CHO clones defective in F...

Topics

Animals
CHO Cells
Cricetinae
Fibrinogen
Fibronectins
Mice
Mice, Inbred BALB C
Mice, Nude
Neoplasms, Experimental
Phenotype
Receptors, Fibronectin
Transfection
von Willebrand Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8375928
DOI: 10.1002/ijc.2910550319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8375928-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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